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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

TextPride changed its name to Swyft Media and launched a platform that pushes emojis and stickers from new brands into messaging apps. Brands pay for the privilege, as they would with a regular ad campaign.
Elsewhere, Stockholm School of Economics was a big winner, climbing 16 places to 28, not only recording the best year-on-year progression but also recovering from a drop of 11 places last year.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Like air, blue skies treat everyone equally.
Fudan University and Peking University, two prestigious comprehensive universities in China, were ranked fourth and sixth on the salary ranking, while the remaining of the top 20 were dominated by finance/economics and science/technology schools.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 促人口要素在城乡间自由流动
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

他们两个自称拥有着世界上最大的两个粉丝基础。但是周日晚上,在伦敦温布利SSE竞技场上举行的2017年欧洲音乐大奖中,Shawn Mendes夺得桂冠, Taylor Swift在她参选的五个奖项中纷纷落选。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 家居“私人定制”行业尚不成熟
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

There are always one or two coworkers in the office that most people can't stand. But if you don't like most of your coworkers, chances are your days aren't very enjoyable because you have to work with them day in and day out. If you can't stand most of your coworkers, it's time to think about finding a company whose employees you mesh with better.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

The Death Proof star's early success was on the independent film circuit. But then she met Harvey Weinstein in a hotel room and it is there that she alleges he raped her.
合作公寓和共管公寓
今年年初,所有华尔街经济学家都呼吁提高利率,彭博社就这个问题调查了67位经济学家的意见,他们全票赞同,有鉴于此,任何一个有理性的人都不会想要增持对利率敏感的公用事业股。把赌注押在金融股上的投资者,回报进展缓慢;而瞅准了“低价”能源股的投资者,投资组合业绩在第一和第二季度曾因此推高,却在第三和第四季度被大拖后腿,可谓“成也萧何,败也萧何”。
A Honda executive privately attributed much of its troubles on “bad luck,” as opposed to shoddy business practices or deliberate misbehavior on anyone’s part. Perhaps. The company’s leadership is certain to check, double-check and lock down its systems and processes to ensure the level sinks no lower on its reservoir of good will.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

n. 回想,记忆,纪念品
目前已经被泄露的照片多达10个G。据《北京日报》12月1日报道,著名在线P2P借贷平台"借贷宝"也和此次事件有关。
In early 2005, Stone and her co-founders Elisa Camahort Page and Jory Des Jardins noticed that there were countless women blogging, but mainstream media rarely linked to their posts. The trio decided to host a grassroots conference that year and attracted sponsors like Google and Yahoo. It quickly sold out and soon after, they launched BlogHer.com. The publishing platform turned blogging into a lucrative business for many women -- it paid $25 million to 5,000 of its bloggers between 2009 and 2012 -- and now reaches an audience of 92 million.
如果他赢得初选,他将与59岁的共和党第一届州长菲尔·斯科特对决。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

如果你已经为人父母,我能够理解,这是不太可能的。你会将孩子放在更重要的位置。但是,如果你没有在课堂上展示自己,那么你也就没有做到我们在第一点里讨论的内容。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

这就真相了,我同意。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Mr Draghi hit back the day after the December vote, saying that there was no “limit” to what eurozone policymakers could do to return inflation to its target.
supervision

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

President Barack Obama won re-election to a second term in the White House on Tuesday, television networks projected, beating Republican challenger Mitt Romney after a long and bitter campaign。
冲击奖项:在最佳女主角的最热人选弗兰西斯麦克多蒙德面前,莎莉霍金斯的获奖几率很小。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 厨电成精装修房屋软肋
Open Access Review Article

Diagnostic technologies for COVID-19: a review

另有其他四部国产电影挤入榜单前十位,排名第三的是《羞羞的铁拳》,第四名为《功夫瑜伽》,第五名为《西游伏妖篇》,第八名为《芳华》。
The untitled movie revolves around two intersecting love triangles, obsession and betrayal, set against the music scene. It stars Christian Bale, Cate Blanchett, Michael Fassbender, Ryan Gosling, Rooney Mara and Natalie Portman.

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 大病保险报销比例由50%提高至60%
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

n. 繁荣,兴旺
7.Morocco
n. 衰微,跌落; 晚年
That deceleration could prove a spoiler to broader growth if it continues apace, as observers have attributed sustained activity growth among manufacturers to stronger domestic demand.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 全国建材家居巨头长沙论剑
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

As per their findings, the recovery mechanism based on reset SMS codes recorded a success rate of 81%, while the method relying on backup emails proved to be efficient in 75% of the cases.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

It is the thirdhighest overall behind the two Indian management academies at Ahmedabad and Bangalore, with respective salaries of $109,000 and $106,000.
adj. 版权的

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

221位去年上榜的富豪今年跌出榜单,有198位富豪首次入选,去年榜单上有29人去世,今年则有29位重返榜单之人。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

“我们内地的执法太不严了,一帮导演到了新加坡不敢抽烟,可是到了珠海,在有警告的情况下依然抽!所以我们的执法一定要严!”

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

adj. 年长的,高级的,资深的,地位较高的
The crown passed from the Plantagenet dynasty to the Tudor monarchs who painted Richard as a deformed villain who stopped at nothing in his quest for power, even murdering his two young nephews -- the so-called Princes in the Tower -- to secure the throne.
I know this takes time, but it'll ensure you really know your stuff. And that's why you're going to school. Right?
Singer Susan Boyle came undone -- literally, when her trousers popped open at a soccer match as she waved a Celtic fan above her head in Scotland. The "Britain

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

[k?n'tinju?s]
以人民币计算,12月份出口环比成功增长0.6%,超过了收缩0.1%的预期,不过仍大大低于11月份5.9%的增幅。以人民币计的进口增长10.8%,是预期4.8%的增幅的两倍以上,不过仍比上个月低2.2个百分点。
全球新职介绍公司Challenger Gray & Christmas 的执行总裁John Challenger 说:“经济不景气之后,总会有个就业复苏期,但是我们的确对2010年的就业率不抱多少乐观态度。”
While newcomer to the list Ariel Foxman, who was appointed managing editor at Time Inc.’s In Style in September 2008, isn’t a regular on a television show as of yet, his fashion director Hal Rubenstein is now a judge onLifetime’s Blush: The Search for the Next Great Make-up Artist. And Foxman’s publication led the way in number of advertising pages, boasting over 1,000 during the first half of 2009.
Be passionate about learning.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

They're developing a core and sorting through roles. Because they're the Lakers, there remains the possibility that a solid free agent or two will look their way.
11月份,财新赞助的中国综合PMI指数读数为50.5。这是自7月份以来,该指数首次超过50这个区分收缩和扩张的荣枯线。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

"If it (transforming the economic development mode) only results in empty talk instead of being implemented, then economic development cannot be promoted in a sound and rapid way, and may even not be sustained." LI YIZHONG, member of the CPPCC National Committee and former minister of industry and information technology

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

体育在热门趋势搜索排行中占据了优势地位,对2012欧洲杯和奥运门票感兴趣的人最多,排名超过了休斯顿和凯特王妃。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

超八成中国留学生会在国外完成学业之后归国,而2016年我国留学生的数量达到了544500人。
Celebuzz has pulled together some of the best snaps of celebrities who go pumpkin picking.Have a look now in the gallery above, then tell us: Are you ready to celebrate Halloween on Wednesday?
Trailing China in 2015 was the UK with $1.9 billion, Japan, $1.8 billion, India, $1.6 billion, and South Korea, $1.5 billion.
6.The Conjuring 2:The Enfield Poltergeist

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

In this ranking of 90 European business schools, Insead in France leads the field for full-time and EMBA programmes, while the University of St Gallen in Switzerland is top for MiM. Iese of Spain and IMD of Switzerland were ranked number one for customised and open-enrolment executive education programmes respectively.
如下是我们对中国2014年的10个预测
沪深300指数(CSI 300)包含了沪深两市交易的300支主要A股,其于2016年交易首日下跌7%,根据新推行的市场熔断机制,意味着当日股市交易已结束。
Not because I am happy to see the end of what was one of television’s smartest series, a pioneer of what is now generally accepted as the current golden age of small-screen serials.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Christine Lagarde, managing director of the International Monetary Fund, said apart from the recovery she expected this year, she was concerned about two other “Rs”. The first was “risks” where she thought some old risks such as the need to finalise financial sector reforms were as important as risks over US tapering, and new concerns such as deflation in the eurozone.
公关行业胜在连基本的发邮件、说话和开会都能玩出无穷的花样。入围作品有:“我想跳上你的雷达”(别,你要跳上来雷达就完了)还有“我们找时间联系,相互更新一下情况”。我最喜欢的是这个,一位名叫迈克尔的这样写道:“希望你别介意这次广推(outreach)。”哎吗,我很介意。主动凑上去(reach out)已经够让人腻歪的了,就算你把它当名词使,还颠倒了词序,也并没啥用好吗。迈克尔,“沟通杯”(Communications cup)归你了。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Tinashe featuring Devonté Hynes “Bet” (RCA)
“由于这些情况不会一夜间消失,2017年贸易基本没有希望复苏,”里尔宁说。
We will weave a strong safety net to ensure people's wellbeing.
6. You dressed 10 times nicer than usual yesterday。
The 22-year-old Lawrence is the face of "The Hunger Games" franchise, and she may earn an Oscar nomination for her performance in "Silver Linings Playbook."

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

?Bond is by no means a comedian but he knows the power of a well-timed one liner. Women are attracted to funny men because humor is a sign of intelligence. You can even predict how many women a man has slept with by how funny he is.
Given that Dallas resisted tanking for years as Dirk Nowitzki's career has wound down and therefore has a fairly limited collection of young talent, adding the 22-year-old Noel without doing any major damage to its rotation counts as a smart play.
税:每年大约18036美元(约合人民币11.5万元)。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

在观影从始至终,我都在问自己一个问题:这部电影到底在讲什么……这部电影的主题仿佛一锅杂烩,并不明晰。我希望制片人也在问同样的问题。
米拉?库妮丝排名第二,其后是凯特?阿普顿、流行歌星蕾哈娜和艾玛?斯通。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Rossi, 31, spends his days calculating the future costs of the Pentagon's pension, health and education benefits, but says his job involves more than just crunching numbers for spreadsheets. He communicates with other government agencies and brainstorms with colleagues about financial models.
Technology and telecoms are on the up as are some fast food companies, including Starbucks, which BrandZ puts in this category, and McDonald's, whose brand value is risen by nine per cent even though its ranking is unchanged.
intel在…中间+lig选择,收集+ence→从中选出好的→智力;聪明

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Fiat will seek to renegotiate the terms of its investment in Chrysler.
由于今年是意大利标志性导演米开朗基罗·安东尼奥尼逝世10周年,为向大师致敬,将放映他的13部经典作品--从他的出道作品《某种爱的记录》到1995年的爱情片《云上的日子》。
2010年10年期美国国债收益率年终收盘报:5.0%。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Song “Embrace Happiness”(Kelly Chen)

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

infection

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

5. Fan Bingbing - $17 million
“我不知道发生了什么”洛瑞说。“我只知道我被吹罚了一次进攻犯规,就这么发生了。这就是NBA,这就是我想说的。”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

André Aciman’s 2007 novel has spawned a big screen adaptation that’s among the most acclaimed films of the year. Up-and-coming 21-year-old actor Timothée Chalamet plays a young man living in Italy who has a passionate affair with an older academic (Armie Hammer). When it premiered at the Sundance Film Festival in January, BBC Culture critic Sam Adams awarded Call Me By Your Name five stars and praised Chalamet and Hammer’s chemistry, the lush photography of the sun-kissed Italian setting, and the particular nuance and depth of the script. It will be a major Academy Awards contender. Released November 24 in the US. (Credit: Sony Pictures Classics)
Tracey and Viv Williams, a British couple, dressed as the green cartoon ogres from Shrek at their wedding held recently. Tracy, 33, made a lovely Princess Fion
Baoneng is believed to have borrowed heavily to fund its share purchases in Vanke and is now the developer’s largest single shareholder with a 25 per cent stake.
人类活动造成的这些气体及其他气体的增加,导致地球温度与前工业化时代相比,上升了大约1.5华氏度(约合0.8摄氏度),造成全球陆冰融化。海平面上升的速度似乎正在加快,热浪和暴雨天气越来越多。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

据行业估计,到2020年,我国年度票房有望达到1000亿元人民币。
McGowan has also hit out at Meryl Streep, saying that it is 'literally impossible' the actress knew nothing of Weinstein's sexual proclivities until last autumn.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

年龄对詹姆斯仍不是问题
单词encourage 联想记忆:

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 北京:物业企业失信行为首次公布
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

According to Feng Zhenglin, head of the Civil Aviation Administration of China, weather accounted for 56.8% of flight delays in 2016, up from 29.5% the previous year.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 关注“中国国际门窗城”
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

The second chart shows the real federal funds rate (ie discounting for inflation) and the real natural rate. Again, when the federal funds rate is above its natural rate, EM crises are more common.
今年时装周预计在今年9月14日至18日举行,在此之前,由歌手帕洛玛费斯撰写并由善待动物组织出版的公开信中呼吁伦敦时装周和英国时装协会禁止动物皮草的使用。
The first view is that the price is inherently cyclical. What has come down must go back up again and the deeper the trough the higher the next mountain.
你要去里约看奥运会吗?你会在安卓或者iOS上装谷歌地图这个应用软件吗?我想你已经有了答案了。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

当时的杜兰特身高6尺9寸,体重只有185磅,我很惊讶在高中赛打到一半时他没有被撞坏。幸运的是,杜兰特不靠在大前锋位置上力量抗衡赚钱,他主要依赖他拿手的急停跳投。
over $50,000 category, pickups and SUVs distributed through non-premium dealers outsell German luxury brands.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 建陶产业链上游企业待解回款难题
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

He admitted to having mixed emotions about the letter as he and Vonnie are now divorced.
但现实远比他想象的艰难。雷文斯克罗夫特表示:“我曾以为这就是一个机会,要花掉两年,但现实是严峻的,因为这活不好干。”此外,他的导师在雷曼兄弟(Lehman Brothers)工作,这家银行于2008年破产。他大笑着说:“这段指导关系持续的时间没有我希望的那么长。”
Are the political upheavals of 2016 — Brexit and America’s election of Donald Trump — a triumph of democracy or a threat to it? Democracies must respond to legitimate grievances.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

PRRI研究总监丹尼尔-考克斯说,一些受访者(包括75%的非白人新教徒)相信恶劣天气既是末日论的证据,也是气候变化的结果。
But whether another hit product can emerge to fend off questions about Apple’s life after Jobs, Mr Cook learnt long ago to be patient and trust his instincts, just as he did when he ignored the doubters to join the then-struggling company in 1998.
Coordinated reform of medical services, medical insurance, and the medicine industry

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

《江南Style》击败《Call Me Maybe》成为最受热捧的流行歌曲,而《007:天降杀机》战胜了《普罗米修斯》成为最多人查询的电影。
adj. 乐观的,乐观主义的

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

vt. 妥协处理,危
农业原材料,特别是所谓的软性大宗商品,例如糖、咖啡和棉花,今年的表现在最佳之列。
It was therapeutic for Warriors fans after enduring the agony of the worst collapse in Finals history the year before, but even then, the whole thing felt like "yup, this is what's supposed to happen." There was very little drama, very little debate, and in the end, the result everyone was sure of happened. That doesn't generate a lot of conversation or interest. It just kind of is what it is.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Nigel Farage, former leader of the UK Independence party, has not advanced so far because it has proved harder to capture the UK’s party-based institutions than it is the US presidency.
在佛罗里达州博卡拉顿林恩大学的辩论,在外交政策和安全上奥巴马有一个固有的优势。作为总统,能接触到情报分析员、外交官和将军的每日简报,他能更好的概括,好像在上半场的辩论中他支配着罗姆尼。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

In his annual news conference with international reporters, Putin said he is ready to work with any president the American people elect.
summary
穆里埃塔属于一个叫“五皇后”的黑帮,他们是加州淘金热的高潮期间,臭名昭著的土匪。虽然穆里埃塔的犯罪行为可能没有任何政治色彩,他还是随着来到加州投机的美国定居者,成了墨西哥抵抗的象征。对他而言,这可不是什么好事,而是促使政府悬赏他的人头,导致他被杀和斩首。幸运的是,班德拉斯的角色没有遭到同样的命运。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

A型与B型人格理论指出,A型人格的人外向、野心勃勃、严谨、地位意识强、敏感、不耐烦、焦虑、积极主动和注重时间管理。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

The French president would have ranked much higher had he not taken a 30% pay cut on assuming office in 2012.
根据弗雷斯特研究公司(Forrester Research)的预测,今年美国网络商店的销售额将达到2,940亿美元,约为全国零售总额的9%。据弗雷斯特预计,到2018年,电子商务将占到全美零售总额的11%,约4,140亿美元,其中通过平板电脑和智能手机进行的交易约占线上销售额的20%。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

2)我相信你的判断:这句话的言外之意:“你征得了我的许可。我信任你。好吧,去做吧。”听到这样的话,是不是感觉很振奋?我保证你会为说这种话的人赴汤蹈火,因为这些话让人感觉如此振奋。你的员工也罢,你的同僚也罢,效果没有区别。
优化区域发展格局。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The Lost Tomb
The Bulls get the Kings' pick if it falls outside the top 10, so it's better for the Kings to be a bottom-10 team than to just miss the playoffs in terms of team-building.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

2017年排行榜分别评选了60个“无工作经验要求”的项目和6个“有工作经验要求”的项目。“无工作经验要求”的项目主要面向拥有很少或没有金融业背景的学生,“有工作经验要求”的项目针对的是已经在金融领域工作的专业人士。只有少数几家学院提供“有工作经验要求”的课程。
得益于网络游戏产业的快速增长,网易公司创始人丁磊的财富翻倍至960亿元,超越了百度公司董事长李彦宏,在IT富豪榜上排名第三。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

自2005年首次发布这一排行榜以来的一项最重大计算方法变化是,FT现在收集校友毕业后首份工作的信息。这些数据与他们当前的工作(毕业三年后)的信息一起使用。这使得FT可以计算出他们自毕业以来的工资增长(一个新的排名指标)以及他们的职业发展。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

supervision
adj. 仁慈的,(为)慈善事业的,宽恕的
如果你觉得现在的杜兰特骨瘦如柴,那你得瞧瞧他在蒙特罗斯基督教会学校时的瘦弱身板。
詹姆斯也反映出了一种趋势,从邓肯到马努·吉诺比利再到文斯卡特,也都是这样。调理、人体健康科学和营养正在为运动员们铺平道路,保持他们的身体素质,使得他们可以打更多的比赛。或许,在他36岁的时候,詹姆斯仍会是球队中最好的球员,即便现在看来这很疯狂。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Of the 27 provincial-level regions that outpaced the country's 6.7% GDP growth in 2016, only three regions - Chongqing, Guizhou and Tibet - achieved double-digit growth.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

By the end of 2015, Shanghai's population of migrant residents had decreased to 9.8 million, comprising 40.6 percent of the city's roughly 24 million permanent residents, according to statistics released by the Shanghai Municipal Statistics Bureau on Monday.
一些深受喜爱的电视剧角色就像老朋友一样存在于我们的生活中,并对我们产生翻天覆地的影响。我们为之捧腹大笑,也为之潸然泪下,甚至不惜撒谎请假,只为能够端坐在电视机前得知他们的最新进展。自始至终,我们对他们如痴如醉。但是还有很多东西是观众无法从银幕上得知的,比如隐藏在这些电视剧中的小秘密。下面就是一些受人追捧的电视剧的幕后故事。
理查三世的遗骨将在当地教堂被正式重新埋葬。他一直被视为英国历史上最残酷的暴君之一,威廉-莎士比亚将其刻画为“驼背的暴君”。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

The reading represented a fall of 0.4 points from September and a sub-index on output for the gauge, which primarily tracks larger and state-owned enterprises, fell 1.3 points to 53.4. That for new orders dipped 1.9 points to 52.9.
The Queen would have been down the stairs like a shot as soon as the aircraft came to a final halt.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 8个词,数尽中国家具8年沉浮
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

今年初,麦基在接受媒体采访时说:“虽然似乎有悖于直觉,但尽可能提高长期利润的最佳途径就是不要把利润作为公司的首要目标。”
这一奖项于3月14日在阿姆斯特丹公布,是基于对全球上百万名旅客的调查而选出的。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

"Apple, Google and Coca-Cola are the most valuable brands as their finances are strong, their brand is a powerful driver of choice and they are very strong compared to competitors," said Jez Frampton, Interbrand's global chief executive officer.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

当她的妈妈来到学校整理她的遗体时,其他的同学把自己的名字和电话号码给了这个悲伤的女人,要求她联系自己的父母,让他们脱离这个网瘾训练营。网瘾训练营其中一种实践方法就是限制学生与外界接触。它是通过基于恐惧的培训方式和严苟的纪律来“纠正”学生行为的。
国家卫生健康委员会补充称,其中81.8%的新病例是同性恋行为造成的,这是由于学生“尽管对疾病有很高的认识,但对保护的意识不强”。
智能开瓶器

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

新年英文祝福语大全
D型人格的人通常自尊心不足,害怕被反对。这也是他们不想向其他人敞开心扉的主要原因。
国际消费类电子产品展
3. You support the teams that I support.

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 中国经济开启湾区化增长之路
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

不要在月薪上撒谎。即使你的上任老板没告诉我们(大多数情况都是这样),我们还是会弄清楚的。我还因此开除掉两名员工。
8. 赤脚能够提高记忆力

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

美国各地许多餐馆和商店星期三向美国退伍军人提供免费服务或优惠,以纪念一年一度的退伍军人节。
Thank you to Aicha Nezzar for sharing this gem on the Facebook Group- Global English Forum.
明尼阿波利斯(MINNEAPOLIS)

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

给你我无尽的新的祝福,让它们成为我们永恒友谊的新的纪念。
Please accept my sincere wishes for the New Year. I hope you will continue to enjoy good health.

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